Magnitude

Evolved from Maggie, Magnitude is a cartridge-based autoinjector enabled by Needle Isolation Technology (NIT) for a more adaptable path into large-volume self-injection. 

Magnitude 3.0 mL and 5.0 mL cartridge-based autoinjectors by SHL Medical
Built for demanding large-volume delivery

Magnitude is designed to provide formulation adaptability, delivery flexibility, and an intuitive self-injection experience.

When more matters

Magnitude is designed to balance the demands of large-volume drug delivery by accommodating program requirements, supporting a practical handheld self-injection experience, and providing a path toward commercial readiness.

Adaptable for evolving formulations

By combining NIT with a cartridge-based design, Magnitude provides formulation and delivery flexibility to accommodate evolving therapy needs.

Magnitude cartridge with a pre-attached needle using Needle Isolation Technology (NIT)

Familiar format for large volume delivery

With a more compact route to large-volume self-injection and a familiar, intuitive push-to-inject operation, Magnitude supports a practical user experience.

Hand placing a Magnitude autoinjector into automated manufacturing equipment

Strong partnership ecosystem

Our established industry partnerships across the value chain support Magnitude from development through commercial manufacturing.

Business handshake representing SHL Medical's industry partnerships

Greater flexibility with market-proven NIT

NIT is SHL Medical's proprietary pre-attached needle technology for cartridge-based delivery. It enables delivery parameter optimization to help support target injection characteristics while eliminating the need for manual needle attachment.

Adaptability to match your delivery needs

The needle is independent of the primary container, which enables the ability to configure the cannula gauge and length to support target injection time and injection depth as per your therapy need.

Practical injection times

NIT’s new innovative technology allows for faster injection times.*

 

*compared to Special Thin Wall cannula of the same gauge

Broader formulation compatibility

NIT enables cartridge-based delivery, helping address formulation considerations associated with siliconized containers and tungsten exposure. Needle isolated until injection further helps protect sensitive formulations from the shelf-life risks inherent to staked-needle systems.

Double-blind trial flexibility

Support device blinding via non-patient contacting needle, simplifying a process that often requires major device or container modifications.

Animation of Needle Isolation Technology (NIT) revealing a 23G to 29G pre-attached needle inside the Magnitude needle cover

Specifications

Viscosity
Low
Volume
3.0 mL and 5.0 mL
Device type
Disposable autoinjector
Primary container
Cartridge with pre-installed needle (NIT)
Route of administration
Subcutaneous
Dosage type
Fixed | Optional automated priming and titration
Activation method
Needle cover
Injection feedback
Continuous audible clicks, viewing window
Customization
Yes
Download specifications

Related resources

The listed resources feature Maggie, which has now evolved into Magnitude. 

Enlarging the volume of subcutaneous autoinjections
Enabling large-volume/high-dose subcutaneous autoinjections
Upsizing autoinjectors for patient independence with new treatments

Get in touch

Connect with us to explore how Magnitude can support your large-volume delivery needs from early development through commercial manufacturing.